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It has been in style for a long time in chilly areas resembling Northern France - Brittany (savory buckwheat crepes are their speciality), Russia (the little pancakes often called blinis were traditionally made with buckwheat), and Northern China - later launched to Japan, (soba noodles).

Among them we identified histone H3 lysine 27 acetylation (H3K27Ac) as a modification upregulated in CRC