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Frequent posttranslational modifications embrace methylation of the ε-amino group, giving methyl- , dimethyl- , and trimethyllysine The latter occurs in calmodulin Other posttranslational modifications at lysine residues embody acetylation , sumoylation , and ubiquitination Collagen accommodates hydroxylysine , which is derived from lysine by lysyl hydroxylase - Glycosylation of hydroxylysine residues within the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell In opsins like rhodopsin and the visual opsins (encoded by the genes OPN1SW , OPN1MW , and OPN1LW ), retinaldehyde kinds a Schiff base with a conserved lysine residue, and interplay of light with the retinylidene group causes sign transduction in coloration vision (See visible cycle for details).
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Kalogeropoulou D, LaFave L, Schweim Okay, Gannon MC, Nuttall FQ: Lysine ingestion markedly attenuates the glucose response to ingested glucose without a change in insulin response. Provided that larger doses could also be required, future studies are needed to guage whether or not the risk of gastrointestinal distress may outweigh the therapeutic advantage of lysine ingestion. Some of these important amino acids corresponding to Lysine and Tryptophan may look acquainted.
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