hbr.orgMethylation been discovered on a spread of lysine residues in numerous histones: K4 (utilizing the one-letter amino-acid code for lysine), K9, K27, K36 and K79 lawyer in my area histone H3, K20 in histone H4, K59 within the globular area of histone H4 2 and K26 of histone H1B 3 A number of proteins responsible for the methylation of specific residues have been characterised, and all but one in all these comprises a SET area